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8): 1. 4 Human Repair Deficiency Disorders Disease Xeroderma pigmentosum Ataxia telangiectasia Trichothiodystrophy Fanconis anemia Blooms syndrome Nijmegen breakage syndrome Werner Syndrome ATLD A-T like disease Characteristics UV sensitive Sensitive to alkylating and cross-linking agents, defective NER Radiosensitive, sensitive DNA breaking agents, defective DNA damage signaling Excision repair deficiency Deficient DNA cross-link repair Deficient double-strand break repair High-level sister chromatid exchange DSB repair.

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